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2024 Impact Factor of CJCR: 6.3
Journal Citation Reports ™, Clarivate Analytics

Temporal trends, disease burden and attributable risk factors of stomach and colorectal cancers among 31 countries and territories in Western Pacific region, 2000−2021

Stomach cancer (SC) and colorectal cancer (CRC) present significant public health challenges because of their high incidence and mortality. According to the International Agency for Research on Cancer (IARC), more than 968,000 new cases and nearly 660,000 deaths of SC occurred in 2022, ranking the cancer as fifth in terms of both incidence and mortality worldwide. Among the six WHO regions, the Western Pacific region (WPR) suffered from the heaviest burdens of SC and CRC.

Global, regional, and national burden of colorectal cancer, 1990−2021: An analysis from global burden of disease study 2021

Data on the global, regional and national changes in the trends of colorectal cancer (CRC) are analyzed to understand the trends in its burden, in order to assist policymakers in allocating healthcare resources and developing prevention and control strategies. Referring to the latest data from the GBD 2021, this study quantifies the impact of different factors on the global, regional, and national burden of disease associated with CRC, and focuses on the differences in the burden of CRC across different SDI regions as well as across different age groups. This study was conducted to rationally allocate medical resources and optimize preventive strategies based on the analysis of the results.

Artificial intelligence efficiently predicts gastric lesions, Helicobacter pylori infection and lymph node metastasis upon endoscopic images

Artificial intelligence has been widely applied in analysis of medical images, including computed tomography images, endoscopic images, histological images, and organoids images. In the current research, the performance of 14 convolutional neural network models was explored for classification and prediction of endoscopic images from human stomach. The purpose is to improve diagnostic accuracy and working efficiency. By training and comparison, EfficientNetB7 revealed the best performance on two-category of gastric cancer and benign lesions, gastric ulcer and ulcerated cancer, as well as early gastric cancer and non-gastric cancer. The EfficientNetB7 was also suitable for predicting the infection of Helicobacter pylori (Hp) and non-Hp infection (noHp). Notable, the InceptionV3 model was capable of predicting perigastric lymph nodes metastasis from endoscopic images.

IMpower210: A phase III study of second-line atezolizumab vs. docetaxel in East Asian patients with non-small cell lung cancer

Non-small cell lung cancer (NSCLC) accounts for more than 80% of all lung cancers, with most patients presenting with advanced or metastatic disease. Lung cancer incidence is particularly high among Asians, who constitute approximately 50% of the global cases. This study reports the results from the phase III IMpower210 study, which compared the efficacy and safety of atezolizumab monotherapy with those of docetaxel in East Asian patients with advanced or metastatic NSCLC who had experienced disease progression with platinum-based chemotherapy. IMpower210 did not meet its primary efficacy endpoint of OS in the ITT EGFR-WT or overall ITT populations. Atezolizumab was comparatively more tolerable than docetaxel, with a lower incidence of grade 3/4 TRAEs.

Plant-based dietary patterns and risk of esophageal cancer: A prospective cohort study spanning 17 years

Plant-based diets have multiple health benefits for cancers; however, little is known about the association between plant-based dietary patterns and esophageal cancer (EC). This study presents an investigation of the prospective associations among three predefined indices of plant-based dietary patterns and the risk of EC. It performed endoscopic screening for 15,709 participants aged 40−69 years from two high-risk areas of China from January 2005 to December 2009 and followed the cohort until December 31, 2022. This study proves that a healthy plant-based dietary pattern was associated with a reduced risk of EC. Emphasizing the healthiness and quality of plant-based diets may be important for preventing the development of EC.

National Health Commission guidelines for diagnosis and treatment of colorectal cancer 2023 in China (English version)

National Health Commission of the People’s Republic of China; Society of Oncology, Chinese Medical Association

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Vol 38, No 1 (Feb 2026)

Consensus and Expert Recommendation

Expert consensus on multidisciplinary management of laparoscopic-endoscopic cooperative surgery combined with sentinel lymph node navigation surgery for early gastric cancer (2026 edition)

Zhi Zheng, Yu Zhao, Rui Xu, Zimeng Wang, Jie Yin, Fandong Meng, Kuiliang Liu, Guangyong Chen, Jun Zhang, Peng Li, Lin Chen, Zhongtao Zhang, Shutian Zhang, National Clinical Research Center for Digestive Diseases, National Key Laboratory of Digestive Health, Digestive Endoscopy Branch of Chinese Medical Association, Gastroenterologist and Hepatologist Branch of Chinese Medical Doctor Association, Chinese Gastric Cancer Association of China Anti-Cancer Association

Pages: 1-26 HTML

Original Article

Evaluating diagnostic efficacy of multigene testing in non-diagnostic thyroid nodules by fine-needle aspiration cytology: A prospective cohort study

Guozhi Zhang, Lin Ren, Jia Xiao, Yangqiu Bao, Hao Tian, Qiyun Shi, Chunlin Tang, Ping Chen, Yan Liang, Peng Tang, Wenting Yan, Ye Zhang, Xiaowei Qi, Yanli Guo, Yi Zhang

Pages: 27-38 HTML

Chemotherapy-free regimen: Real-world efficacy and safety of anlotinib plus PD-1/PD-L1 inhibitors in advanced non-small cell lung cancer

Haiyang Chen, Guanghua Yang, Tao Wang, Gongbin Chen, Aiguo Xu, Chunzheng Ma, Ke Shang, Peijie Liu, Honglin Zhou, Zhiwei Wang, Xinju Xu, Xiao Sun, Fengyu Zhai, Yuanyuan Ji, Juan Huangfu, Xinli Jia, Chunqing Li, Jiazhuan Mei, Minyong Jia, Shunhai Niu, Gaogao Zhang, Yuqing Liu, Lin Lu, Juntao Zhang, Lijun Wang, Tianjiang Ma, Liwei Gao, Cailing Jin, Qiming Wang

Pages: 39-51 HTML

Dynamic income patterns and risk of pancreatic and biliary tract cancers: A nationwide cohort study

Chung-woo Lee, Kunhee Han, Yong-Moon Mark Park, Ju-Yeong Park, Kyu-Na Lee, Dong Wook Shin, Seon Mee Kim, Youn Seon Choi, Kyungdo Han, Ga Eun Nam

Pages: 52-66 HTML

Circulating tumor cells with chromosome 8 aneuploidy are a diagnostic and prognostic monitoring biomarker for ovarian cancer

Shimin Yang, Buyun Li, Hongyan Cheng, Xue Ye, Sha Dou, Yuanfen Wang, Xuelian Song, Huarui Yang, Xiaohong Chang, Yi Li

Pages: 67-82 HTML

Chromatin regulators TOP2A and PPARGC1A stratify prostate cancer risk and reveal TOP2A-driven progression via PI3K/AKT pathway

Zhipeng Wang, Jie Wang, Shuang Chen, Ruicheng Wu, Zhouting Tuo, Luxia Ye, Koo Han Yoo, Dengxiong Li, Xiaodong Jin, Wei Xiong, Dechao Feng

Pages: 83-99 HTML

Review Article

Frontiers in bacterial outer membrane vesicles: From basic characteristics to cancer therapy

Siyang Ma, Jianxuan Sun, Jingyu Xu, Ye An, Jinzhou Xu, Shaogang Wang, Qidong Xia

Pages: 100-118 HTML

NHCPRC Guidelines

National Health Commission guidelines for diagnosis and treatment of colorectal cancer in China (2025 edition, English version)

Department of Medical Administration, National Health Commission of the People’s Republic of China; Chinese Medical Association Oncology Branch

Pages: 949-961 HTML

National Health Commission guidelines for diagnosis and treatment of colorectal cancer 2023 in China (English version)

National Health Commission of the People’s Republic of China; Society of Oncology, Chinese Medical Association

Pages: 197-232 HTML