Article Abstract

PRIMARY NEUROENDOCRINE TUMORS OF THE LIVER AND GALLBLADDER

Authors: Jiyao Yu,Ming Hu,Lin Yao

Abstract

To study Clinico-pathological characters of the neuroendocrine tumors of the liver and gallbladder.

Methods: Using histology, immunohistochemistry and electron microscope, 3 cases of liver and gallbladder were investigated. The primary antibodies including antichromogranin A, gastrln, serotonin, insulin, somatustatin, gastrin, pancreatic polypeptide, adreno-corticotropic hormone (ACTH), calcitunin, bombesin, [β-human chorionic gonadotropin (β-HCG) were employed to identify the properly of tumors.

Results: In one cases tumor of neuroendocrine carcinoma. In dae other two cases tumor were typical carcinoid. In immunohistochemistry study, the tumor cells showed positive reaction to ehromagranin A and contained positive cells of gastrin, serotonin, insulin and pancreatic polypaptide. Electronmicroscopy showed the cytoplasm contained dense round granules.

Conclusion: The Nuroendocrine tumor of liver and gallbladder is a special type neoplasm with character of histology, immunohistocbemistry and electron microscopy. Subject headings neuroendocrine tumor gallbladder liver immunohistochemistry and electron microscopy.

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