EXPRESSION OF MOUSE Tbx2 GENE IN NORMAL AND MALIGNANT MELANOPHORES BY RT-PCR
Abstract
Objective: To observe the expression of mouse Tbx2 gene in normal and malignant melanophore.
Methods: The normal and malignant cells were used to extract total RNA. The expression of the Tbx2 gene was detected by RT-PCR.
Results: No expression of the Tbx2 gene in the normal melanocytes was noted, but all malignant cells showed expression of the Tbx2 gene.
Conclusion: Tbx2 plays a critical role during the development of the malignant cells.
Methods: The normal and malignant cells were used to extract total RNA. The expression of the Tbx2 gene was detected by RT-PCR.
Results: No expression of the Tbx2 gene in the normal melanocytes was noted, but all malignant cells showed expression of the Tbx2 gene.
Conclusion: Tbx2 plays a critical role during the development of the malignant cells.