INFLAMMATORY FIBROID POLYPS OF GASTRO-INTESTINAL TRACT
Abstract
Objective: To review the diagnosis and differential diagnosis of inflammatory fibroid polyp (IFP) of gastrointestinal tract.
Methods: The clinical symptoms, histopathologic features and immunohistochemical (ABC method) staining in 9 cases were observed.
Results: IFP presented either as a solitary pedunculated or sessile lesion arising from the submucosa and protroding into the lumen; composed of a background of fibroblasts and blood vessels infiltrated by a variable number of inflammatory cells, often numerous eosinophilias leukocytes. Immunohistochemical staining: the spindle cells of all cases reacted with Vimentin. The partial cells of several cases react with Actin, NSE, o~ - AT. 7 cases were follow-up. No patients had a recurrence of the lesion.
Conclusion: IFP are rare lesions, and may represent an exaggerated response to inflammatory or other injury process. The prognosis is good when treated by segmental resections of endoscopic removals.
Methods: The clinical symptoms, histopathologic features and immunohistochemical (ABC method) staining in 9 cases were observed.
Results: IFP presented either as a solitary pedunculated or sessile lesion arising from the submucosa and protroding into the lumen; composed of a background of fibroblasts and blood vessels infiltrated by a variable number of inflammatory cells, often numerous eosinophilias leukocytes. Immunohistochemical staining: the spindle cells of all cases reacted with Vimentin. The partial cells of several cases react with Actin, NSE, o~ - AT. 7 cases were follow-up. No patients had a recurrence of the lesion.
Conclusion: IFP are rare lesions, and may represent an exaggerated response to inflammatory or other injury process. The prognosis is good when treated by segmental resections of endoscopic removals.