According to the standards of WHO clasification, nasopharyngeal carcinoma (NPC) is originated from the lining epithelium of the nasopharyngeal mucosa and those carcinomas of the nasopharynx, including adenocarcinoma, adenosquamous carcinoma and others are not termed NPCs. NPCs are consistently associated with EB virus. Besides NPCs is there also an association of EB virus with adenosquamous carcinoma? This is unknown. The authors report a case of adenosquamous carcinoma of the nasopharynx herein which contained EB virus.